Polypharmacy - essential, but also to be avoided

Extubation failure: an outcome to be avoided

Extubation failure is an outcome of increasing importance but nearly all studies have been conducted in academic settings. The article by Seymour and colleagues demonstrates that extubation failure is an outcome to be avoided in the community hospital setting as well. Patients failing extubation experience longer lengths of stay, experience higher intensive care unit mortality, and incur greate...

Polypharmacy: Misleading, but manageable

The percentage of the population described as elderly is growing, and a higher prevalence of multiple, chronic disease states must be managed concurrently. Healthcare practitioners must appropriately use medication for multiple diseases and avoid risks often associated with multiple medication use such as adverse effects, drug/drug interactions, drug/disease interactions, and inappropriate dosi...

Extinction tsunami can be avoided.

In many senses, the recent publication in PNAS by Ceballos et al. (1) on population losses and declines in vertebrates can be traced back to efforts early in the 20th century led by the American Committee for International Wildlife Protection to document the extinction phenomenon (2–4). The focus at the time was very much on individual species, not on extinction rates, and certainly not on prec...

criticism sould have to be scaled also publication should have to be valid

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Should Priority Setting Also Be Concerned About Profound Socio-Economic Transformations? A Response to Recent Commentary